Iranian Food Science and Technology Research Journal
with the collaboration of Iranian Food Science and Technology Association (IFSTA)

Biodetoxification of aflatoxin M1 using Lactobacillus acidophilus in simulated gastric model

Document Type : Research Article

Authors

Marzieh Shamshiri
Ali Mohamadi Sani
Mahboubeh Sarabi 1
Paria Rahnama Vosough
Massoumeh Mehraban Sangatash 2

1 Food Science and Technology Research Institute

2 Food Science and Technology Research Institute, ACECR Khorasan Razavi Branch

https://doi.org/10.22067/ifstrj.v10i3.38000
Abstract
Biodetoxification is considered as one of the method for eliminating of aflatoxins including aflatoxin M1 (AFM1). In the present study, the ability of Lactobacillus acidophilus (La-5) in reduction of AFM1 in a simulated gastric model was studied. In this regard, two levels of bacterial suspension (3×109 and 3×1010 cfu/ml) were used to determine their ability to reduce three concentrations of AFM1 (0.05, 0.25 and 0.5 ppb). The incubation times in the simulated gastric model were 0, 30, 60.90 and 120 minutes. AFM1 concentration was determined by competitive ELISA. Results showed that the presence of Lactobacillus acidophilus (La-5) was more effective at higher concentration for removal of aflatoxin. Also, removal content for 0.05, 0.25, 0.5 ppb AFM1 were 76.09, 52.26 and 76.19 respectively.

Keywords

Aflatoxin M1
Biodetoxification
Food Safety
Lactobacillus acidophilus
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  • Receive Date 16 April 2012
  • Accept Date 11 June 2014
  • First Publish Date 23 September 2014

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